RT Journal Article SR Electronic T1 PSF correction in soft x-ray tomography JF bioRxiv FD Cold Spring Harbor Laboratory SP 260737 DO 10.1101/260737 A1 Ekman, Axel A1 Weinhardt, Venera A1 Chen, Jian-Hua A1 McDermott, Gerry A1 Le Gros, Mark A. A1 Larabell, Carolyn YR 2018 UL http://biorxiv.org/content/early/2018/02/05/260737.abstract AB In this manuscript, we introduce a linear approximation of the forward model of soft x-ray tomography (SXT), such that the reconstruction is solvable by standard iterative schemes. This linear model takes into account the three-dimensional point spread function (PSF) of the optical system, which consequently enhances the reconstruction data. The feasibility of the model is demonstrated on both simulated and experimental data, based on theoretically estimated and experimentally measured PSFs.