PT - JOURNAL ARTICLE AU - Ah Jung Jeon AU - David Kellogg AU - Mohammed Asif Khan AU - Greg Tucker-Kellogg TI - Developing critical thinking in STEM education through inquiry-based writing in the laboratory classroom AID - 10.1101/686022 DP - 2019 Jan 01 TA - bioRxiv PG - 686022 4099 - http://biorxiv.org/content/early/2019/06/30/686022.short 4100 - http://biorxiv.org/content/early/2019/06/30/686022.full AB - Laboratory pedagogy is moving away from step-by-step instructions and toward inquiry-based learning (IBL), but only now developing methods for integrating inquiry-based writing (IBW) practices into the laboratory course. Based on an earlier proposal (Science 332:919 (2011)), we designed and implemented an IBW sequence in a university bioinformatics course.We automatically generated unique, double-blinded, biologically plausible DNA sequences for each student. After guided instruction, students investigated sequences independently and responded through IBW writing assignments. IBW assignments were structured as condensed versions of a scientific research paper, and because the sequences were double blinded, they were also assessed as authentic science and evaluated on clarity and persuasiveness.We piloted the approach in a seven-day workshop (35 students) at Perdana University Graduate School of Medicine in Kuala Lumpur. We observed dramatically improved student engagement and indirect evidence of improved learning outcomes over a similar workshop without IBW. Based on student feedback, initial discomfort with the writing component abated in favor of an overall positive response and increasing comfort with the high demands of student writing. Similarly encouraging results were found in a semester length undergraduate module at the National University of Singapore (155 students).