PT  - JOURNAL ARTICLE
AU  - Helen Dolengevich-Segal
AU  - Alicia Gonzalez-Baeza
AU  - Jorge Valencia
AU  - Eulalia Valencia-Ortega
AU  - Alfonso Cabello
AU  - Maria Jesus Tellez Molina
AU  - Maria Jesus Perez Elias
AU  - Regino Serrano
AU  - Leire Perez Latorre
AU  - Luz Martín-Carbonero
AU  - Sari Arponen
AU  - Jose Sanz Moreno
AU  - Sara De La Fuente
AU  - Otilia Bisbal
AU  - Ignacio Santos
AU  - Jose Luis Casado
AU  - Jesus Troya
AU  - Miguel Cervero Jimenez
AU  - Sara Nistal
AU  - Guillermo Cuevas
AU  - Javier Correas Lauffer
AU  - Marta Torrens
AU  - Pablo Ryan
AU  - on Behalf of the U-SEX GESIDA 9416 Study
TI  - Drug related and psychopathological symptoms in HIV-positive men who have sex with men who inject drugs during sex (Slamsex): Data from the U-SEX GESIDA 9416 Study
AID  - 10.1101/703272
DP  - 2019 Jan 01
TA  - bioRxiv
PG  - 703272
4099  - http://biorxiv.org/content/early/2019/07/15/703272.short
4100  - http://biorxiv.org/content/early/2019/07/15/703272.full
AB  - Objectives Intravenous sexualized drug use also known as slamsex seems to be increasing among HIV-positive men who have sex with men (MSM). This practice may entail severe consequences for physical and mental health in this population. Research on the subject is scarce. The aim of our study was to describe the psychopathological background of a sample of HIV positive MSM who practiced slamsex during the previous year and compare the physical and psychological symptoms between these participants and those who practiced sexualized drug use (SDU) or chemsex without slamsex.Design and Methods Participants (HIV-positive MSM) were recruited from the U-Sex study in 22 HIV clinics in Madrid during 2016-17. All participants completed an anonymous cross-sectional survey on sexual behaviour and recreational drug use. The present analysis is based on HIV-positive MSM who had practiced SDU.Results The survey sample comprised 742 participants. Of all the participants who completed the survey, 216 (29.1%) practiced chemsex, and of these, 34 (15.7%) had practiced slamsex. Participants who practiced slamsex were more likely to have current psychopathology (depression, anxiety and drug related disorders) than chemsex users. In addition, participants who practiced slamsex had more high-risk sexual behaviours, polydrug use and were more often diagnosed with sexually transmitted infections (STIs) and hepatitis C than those who did not inject drugs. Compared with patients who did not inject drugs, patients who engaged in slamsex showed more severe drug related symptoms (withdrawal and dependence), symptoms of severe intoxication (loss of consciousness), and severe psychopathological symptoms related to SDU, such as paranoid thoughts and suicidal behaviour.Conclusion Slamsex (intravenous SDU) is closely associated with current psychiatric disorders and severe drug-related and psychiatric symptoms.