RT Journal Article
SR Electronic
T1 A fully automatic method yielding initial models from high-resolution electron cryo-microscopy maps
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 267138
DO 10.1101/267138
A1 Terwilliger, Thomas C.
A1 Adams, Paul D.
A1 Afonine, Pavel V.
A1 Sobolev, Oleg V.
YR 2018
UL http://biorxiv.org/content/early/2018/02/16/267138.abstract
AB A fully automated procedure for optimization and interpretation of reconstructions from cryo-EM is developed and applied to 476 datasets with resolution of 4.5 Å or better, including reconstructions of 47 ribosomes and 32 other protein-RNA complexes. The median fraction of residues in the deposited structures reproduced automatically was 71% for reconstructions determined at resolutions of 3 Å or better and 47% for those at lower resolution.