RT Journal Article
SR Electronic
T1 OMCD: OncoMir Cancer Database
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 279125
DO 10.1101/279125
A1 Aaron Sarver
A1 Anne Sarver
A1 Ce Yuan
A1 Subbaya Subramanian
YR 2018
UL http://biorxiv.org/content/early/2018/03/08/279125.abstract
AB microRNAs (miRNAs) are small non-coding RNAs crucially important in cancer. Dysregulation of miRNAs is commonly observed in cancers and it largely cancer dependent. It is thus important to study pan-cancer miRNA expression in order to develop accurate and sensitive biomarkers. Here, we developed the OMCD - OncoMir Cancer Database, a web server that allows easy and systematic comparative genomic analyses of miRNAs sequencing data derived from over 9,500 cancer patients with associated clinical information and organ-specific controls present in the Cancer Genome Atlas (TCGA) database. The OMCD webserver provides 1). simple visualization of TCGA miRNA sequencing data, 2). statistical analysis of differentially expressed miRNAs for each cancer type and 3). allows for exploring miRNA clusters across cancer types. The OMCD web server is freely available to all users and can be accessed at www.oncomir.umn.edu/omcd/.Database URL: www.oncomir.umn.edu/omcd/