RT Journal Article
SR Electronic
T1 Phage composition of a fermented milk and colostrum product assessed by microbiome array; putative role of open reading frames
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 714154
DO 10.1101/714154
A1 Stefania Pacini
A1 Marco Ruggiero
YR 2019
UL http://biorxiv.org/content/early/2019/08/06/714154.abstract
AB Bacteriophages (phages), Earth’s most numerous biological entities, are natural constituents of alimentary matrices; in this study we describe the characterization of phage populations in a product obtained by fermentation of bovine milk and colostrum. Such characterizations were achieved using a microarray consisting of a chip covered in short DNA sequences that are specific to certain target organisms for a total of approximately 12,000 species. The only viruses evidenced by the array belonged to Siphoviridae, the largest phage family that targets bacteria and archea. The array yielded 27 iterations corresponding to a unique target. We discuss the putative role of some open reading frames of these phages in conferring health-supporting properties.