PT - JOURNAL ARTICLE AU - Mark Lipson AU - Olivia Cheronet AU - Swapan Mallick AU - Nadin Rohland AU - Marc Oxenham AU - Michael Pietrusewsky AU - Thomas Oliver Pryce AU - Anna Willis AU - Hirofumi Matsumura AU - Hallie Buckley AU - Kate Domett AU - Nguyen Giang Hai AU - Trinh Hoang Hiep AU - Aung Aung Kyaw AU - Tin Tin Win AU - Baptiste Pradier AU - Nasreen Broomandkhoshbacht AU - Francesca Candilio AU - Piya Changmai AU - Daniel Fernandes AU - Matthew Ferry AU - Beatriz Gamarra AU - Eadaoin Harney AU - Jatupol Kampuansai AU - Wibhu Kutanan AU - Megan Michel AU - Mario Novak AU - Jonas Oppenheimer AU - Kendra Sirak AU - Kristin Stewardson AU - Zhao Zhang AU - Pavel Flegontov AU - Ron Pinhasi AU - David Reich TI - Ancient genomes document multiple waves of migration in Southeast Asian prehistory AID - 10.1101/279646 DP - 2018 Jan 01 TA - bioRxiv PG - 279646 4099 - http://biorxiv.org/content/early/2018/03/10/279646.short 4100 - http://biorxiv.org/content/early/2018/03/10/279646.full AB - Southeast Asia is home to rich human genetic and linguistic diversity, but the details of past population movements in the region are not well known. Here, we report genome-wide ancient DNA data from thirteen Southeast Asian individuals spanning from the Neolithic period through the Iron Age (4100–1700 years ago). Early agriculturalists from Man Bac in Vietnam possessed a mixture of East Asian (southern Chinese farmer) and deeply diverged eastern Eurasian (hunter-gatherer) ancestry characteristic of Austroasiatic speakers, with similar ancestry as far south as Indonesia providing evidence for an expansive initial spread of Austroasiatic languages. In a striking parallel with Europe, later sites from across the region show closer connections to present-day majority groups, reflecting a second major influx of migrants by the time of the Bronze Age.