RT Journal Article
SR Electronic
T1 Specific Regulation of <em>TCP genes</em> by miR319
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 747790
DO 10.1101/747790
A1 Javier F. Palatnik
A1 Detlef Weigel
YR 2019
UL http://biorxiv.org/content/early/2019/08/28/747790.abstract
AB MicroRNAs (miRNAs) are major regulators of gene expression in multicellular organisms. Many of the evolutionarily conserved miRNAs in plants are encoded by small gene families. The miR159/miR319 family has six members of similar sequences sharing 17 nucleotides in Arabidopsis thaliana. The members of this miRNA family regulate genes encoding TCP (TEOSINTE BRANCHED1, CYCLOIDEA and PCF1/2) and MYB transcription factors. However, despite their sequence similarities, genetic evidence indicates that miR159 and miR319 fulfil different roles in vivo. Here, we confirm previous findings showing that TCP genes are not targeted by miR159. Thus, specific small sequence differences between the miRNAs allow for the specific regulation of TCP transcription factors by miR319 miRNAs.