TY - JOUR T1 - Improved metagenomic analysis with Kraken 2 JF - bioRxiv DO - 10.1101/762302 SP - 762302 AU - Derrick E. Wood AU - Jennifer Lu AU - Ben Langmead Y1 - 2019/01/01 UR - http://biorxiv.org/content/early/2019/09/07/762302.abstract N2 - Although Kraken’s k-mer-based approach provides fast taxonomic classification of metagenomic sequence data, its large memory requirements can be limiting for some applications. Kraken 2 improves upon Kraken 1 by reducing memory usage by 85%, allowing greater amounts of reference genomic data to be used, while maintaining high accuracy and increasing speed five-fold. Kraken 2 also introduces a translated search mode, providing increased sensitivity in viral metagenomics analysis. ER -