PT  - JOURNAL ARTICLE
AU  - Luke C. Pilling
AU  - Lorna W Harries
AU  - Dena G Hernandez
AU  - Andrew B Singleton
AU  - George A. Kuchel
AU  - Luigi Ferrucci
AU  - David Melzer
TI  - The reported healthy ageing gene expression score: lack of predictive value in two cohorts
AID  - 10.1101/034058
DP  - 2015 Jan 01
TA  - bioRxiv
PG  - 034058
4099  - http://biorxiv.org/content/early/2015/12/09/034058.short
4100  - http://biorxiv.org/content/early/2015/12/09/034058.full
AB  - Sood et al. report a multi-tissue RNA signature “predictive of human health, using only peripheral blood samples”. We tested this score in blood in two independent, larger cohorts and found no associations with age or related phenotypes, including strength, interleukin-6 or mortality.A response to: A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status by Sood S, Gallagher IJ, Lunnon K, Rullman E, Keohane A, Crossland H, et al. Genome Biology; 2015;16:185.