RT Journal Article SR Electronic T1 Foundations of human problem solving JF bioRxiv FD Cold Spring Harbor Laboratory SP 779322 DO 10.1101/779322 A1 Noah Zarr A1 Joshua W. Brown YR 2019 UL http://biorxiv.org/content/early/2019/09/23/779322.abstract AB Despite great strides in both machine learning and neuroscience, we do not know how the human brain solves problems in the general sense. We approach this question by drawing on the framework of engineering control theory. We demonstrate a computational neural model with only localist learning laws that is able to find solutions to arbitrary problems. Using a combination of computational neural modeling, human fMRI, and representational similarity analysis, we show here that the roles of a number of brain regions can be reinterpreted as interacting mechanisms of a control theoretic system. The results suggest a new set of functional perspectives on the orbitofrontal cortex, hippocampus, basal ganglia, anterior temporal lobe, lateral prefrontal cortex, and visual cortex, as well as a new path toward artificial general intelligence.