PT - JOURNAL ARTICLE AU - Kamila Mardieva AU - Munira Burkhanova TI - The influence of the supramolecular complex PRE -1 on permeability of membranes of mitochondria AID - 10.1101/300855 DP - 2018 Jan 01 TA - bioRxiv PG - 300855 4099 - http://biorxiv.org/content/early/2018/04/14/300855.short 4100 - http://biorxiv.org/content/early/2018/04/14/300855.full AB - The change in the state of the mitochondrial pore of nonspecific conductivity plays a key role in the processes of triggering and regulating apoptosis. Therefore, the study of mechanisms of opening and regulating the state of these pores can have a great importance to find the ways of correcting many mitochondrial dysfunctions, including those which are associated with age-related changes. In our work, we have done a comparative analysis for swelling of brain mitochondria of adult (9 months) and mature rats (12-15 months).