TY - JOUR T1 - Comment on ‘Multiple Origin but Single Domestication Led to <em>Oryza sativa</em>’ JF - bioRxiv DO - 10.1101/299669 SP - 299669 AU - Peter Civáň AU - Terence A. Brown Y1 - 2018/01/01 UR - http://biorxiv.org/content/early/2018/04/14/299669.abstract N2 - In 2015, we published an analysis of rice genomic data and showed that the japonica, indica and aus groups of cultivated rice were independently domesticated. Our conclusions were controversial as they contradicted a previous, high-profile analysis of the same dataset, which had suggested that all of cultivated rice derives from a single origin. Although there have been attempts since 2015 to bolster the single-origin hypothesis, until recently there has been no direct rebuttal of the methodology that we used to infer multiple origins. Such a rebuttal has now been published (Choi J.Y., Purugganan M.D., 2018 Multiple origin but single domestication led to Oryza sativa. G3 8:797-803), but the reanalysis that is presented only supports the single origin hypothesis if phylogenetic trees that are clearly paraphyletic are interpreted as monophyletic, and furthermore addresses only one component of the evidence that we presented for multiple domestications. We caution against accepting these analyses uncritically. ER -