PT  - JOURNAL ARTICLE
AU  - Khaoula Belhaj
AU  - Liliana M. Cano
AU  - David C. Prince
AU  - Ariane Kemen
AU  - Kentaro Yoshida
AU  - Yasin F. Dagdas
AU  - Graham J. Etherington
AU  - Henk-jan Schoonbeek
AU  - H. Peter van Esse
AU  - Jonathan D.G. Jones
AU  - Sophien Kamoun
AU  - Sebastian Schornack
TI  - Arabidopsis late blight: Infection of a nonhost plant by <em>Albugo laibachii</em> enables full colonization by <em>Phytophthora infestans</em>
AID  - 10.1101/035006
DP  - 2015 Jan 01
TA  - bioRxiv
PG  - 035006
4099  - http://biorxiv.org/content/early/2015/12/23/035006.short
4100  - http://biorxiv.org/content/early/2015/12/23/035006.full
AB  - The oomycete pathogen Phytophthora infestans causes potato late blight, and as a potato and tomato specialist pathogen, is seemingly poorly adapted to infect plants outside the Solanaceae. Here, we report the unexpected finding that P. infestans can infect Arabidopsis thaliana when another oomycete pathogen, Albugo laibachii, has colonized the host plant. The behaviour and speed of P. infestans infection in Arabidopsis pre-infected with A. laibachii resemble P. infestans infection of susceptible potato plants. Transcriptional profiling of P. infestans genes during infection revealed a significant overlap in the sets of secreted-protein genes that are induced in P. infestans upon colonisation of potato and susceptible Arabidopsis, suggesting major similarities in P. infestans gene expression dynamics on the two plant species. Furthermore, we found haustoria of A. laibachii and P. infestans within the same Arabidopsis cells. This Arabidopsis - A. laibachii - P. infestans tripartite interaction opens up various possibilities to dissect the molecular mechanisms of P. infestans infection and the processes occurring in co-infected Arabidopsis cells.