%0 Journal Article %A Chang-Hao Kao %A Ankit N. Khambhati %A Danielle S. Bassett %A Matthew R. Nassar %A Joseph T. McGuire %A Joshua I. Gold %A Joseph W. Kable %T Functional brain network reconfiguration during learning in a dynamic environment %D 2019 %R 10.1101/800284 %J bioRxiv %P 800284 %X In dynamic environments, people should learn faster, adjusting their beliefs more in response to new evidence, either when that new evidence is more surprising and indicative of a likely change in the state of the environment or when their beliefs are more uncertain due to a lack of information about the current environmental state. Here we identified a pattern of whole-brain functional connectivity that changed dynamically over time, being more strongly expressed under conditions of high surprise or uncertainty, and being enhanced in individuals that adapted their learning and belief updating more appropriately in response to these factors. The key features of this whole-brain pattern of functional connectivity involved stronger connectivity, or functional integration, between the fronto-parietal and other functional systems. Our results provide new insights regarding the association between dynamic adjustments in learning and dynamic, large-scale changes in functional connectivity across the whole brain. %U https://www.biorxiv.org/content/biorxiv/early/2019/10/10/800284.full.pdf