RT Journal Article
SR Electronic
T1 Broad geographic sampling reveals predictable, pervasive, and strong seasonal adaptation in Drosophila
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 337543
DO 10.1101/337543
A1 Heather E. Machado
A1 Alan O. Bergland
A1 Ryan Taylor
A1 Susanne Tilk
A1 Emily Behrman
A1 Kelly Dyer
A1 Daniel K. Fabian
A1 Thomas Flatt
A1 Josefa González
A1 Talia L. Karasov
A1 Iryna Kozeretska
A1 Brian P. Lazzaro
A1 Thomas JS Merritt
A1 John E. Pool
A1 Katherine O’Brien
A1 Subhash Rajpurohit
A1 Paula R. Roy
A1 Stephen W. Schaeffer
A1 Svitlana Serga
A1 Paul Schmidt
A1 Dmitri A. Petrov
YR 2019
UL http://biorxiv.org/content/early/2019/10/11/337543.abstract
AB To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. To study these evolutionary dynamics, we estimated allele frequencies genome-wide from flies sampled early and late in the growing season from 20 widely dispersed populations. We identify parallel seasonal allele frequency shifts across North America and Europe, demonstrating that seasonal adaptation is a general phenomenon of temperate fly populations. The direction of allele frequency change at seasonally variable polymorphisms can be predicted by weather conditions in the weeks prior to sampling, linking the environment and the genomic response to selection. The extent of allele frequency fluctuations implies that seasonal evolution drives substantial (5-10%) allele frequency fluctuations at >1% of common polymorphisms across the genome. Our results suggest that fluctuating selection is an important evolutionary force affecting the extent and stability of linked and functional variation.