PT  - JOURNAL ARTICLE
AU  - Ludwig A. Hothorn
AU  - Felix M. Kluxen
AU  - Mario Hasler
TI  - Pseudo-data generation allows the statistical re-evaluation of toxicological bioassays based on summary statistics
AID  - 10.1101/810408
DP  - 2019 Jan 01
TA  - bioRxiv
PG  - 810408
4099  - http://biorxiv.org/content/early/2019/10/18/810408.short
4100  - http://biorxiv.org/content/early/2019/10/18/810408.full
AB  - Sometimes a re-analysis of toxicological data is useful. However, this usually requires the availability of the original data and in many cases only summary data are available in the publications. Here the generation of pseudo-data under certain assumptions using extension packages in the open-source project R on statistical computing is shown. Several case studies are used to illustrate the applicability in regulatory toxicology.