RT Journal Article
SR Electronic
T1 Pseudo-data generation allows the statistical re-evaluation of toxicological bioassays based on summary statistics
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 810408
DO 10.1101/810408
A1 Ludwig A. Hothorn
A1 Felix M. Kluxen
A1 Mario Hasler
YR 2019
UL http://biorxiv.org/content/early/2019/10/18/810408.abstract
AB Sometimes a re-analysis of toxicological data is useful. However, this usually requires the availability of the original data and in many cases only summary data are available in the publications. Here the generation of pseudo-data under certain assumptions using extension packages in the open-source project R on statistical computing is shown. Several case studies are used to illustrate the applicability in regulatory toxicology.