PT  - JOURNAL ARTICLE
AU  - Steven Xijin Ge
AU  - Dongmin Jung
TI  - ShinyGO: a graphical enrichment tool for ani-mals and plants
AID  - 10.1101/315150
DP  - 2018 Jan 01
TA  - bioRxiv
PG  - 315150
4099  - http://biorxiv.org/content/early/2018/05/04/315150.short
4100  - http://biorxiv.org/content/early/2018/05/04/315150.full
AB  - Motivation Gene lists are routinely produced from various genome-wide studies. Enrichment analysis can link these gene lists with underlying molecular pathways by using functional categories such as gene ontology (GO).Results To complement existing tools, we developed ShinyGO with several features: (1) large annotation database from GO and many other sources for over 200 plant and animal species, (2) graphical visualization of enrichment results and gene characteristics, and (3) application program interface (API) access to KEGG and STRING for the retrieval of pathway diagrams and protein-protein interaction networks. ShinyGO is an intuitive, graphical web application that can help researchers gain actionable insights from gene lists.Availability http://ge-lab.org/go/Contact gexijin{at}gmail.comSupplementary information Supplementary data are available at Bioinformatics online.