RT Journal Article
SR Electronic
T1 Comparative of probiotics reveals cecal microbial component associated with performance parameters in broilers
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 846766
DO 10.1101/846766
A1 D.R. Rodrigues
A1 W. Briggs
A1 A. Duff
A1 K. Chasser
A1 R. Murugesan
A1 C. Pender
A1 S. Ramirez
A1 L. Valenzuela
A1 L.R. Bielke
YR 2019
UL http://biorxiv.org/content/early/2019/11/18/846766.abstract
AB Probiotics have become increasingly popular in poultry industry as a promising nutritional intervention to promote modulation of intestinal microbiota as a means of improving health and performance. This study aimed to determine the effects of different probiotic formulations on the cecal microbial communities and performance in 21 and 42 day-old-broilers, as well as to define associations between ceca microbial profile and growth parameters. Probiotics investigated included a synbiotic (SYNBIO), a yeast-based probiotic (YEAST), and three single-strain formulations of spore-forming Bacillus amyloliquefaciens (SINGLE1), B. subtilis (SINGLE2) and B. licheniformis (SINGLE3). Dietary inclusion of SYNBIO, YEAST, and SINGLE2 increased body weight (BW) by 7, 14, and 21d (p<0.05) compared to a basal diet without probiotics (CON). The treatments SYNBIO, and YEAST decreased mortality by 21d, while SYNBIO reduced the overall mortality rate by 42d (p<0.05). Bifidobacteriales had the highest (p<0.05) population in SINGLE2, whereas Clostridiales was reduced compared to CON, SINGLE1, and SINGLE3. The addition of SYNBIO into diet mainly stimulated (p<0.05) the cecal relative abundance of Lactobacillales by 21d. Besides, Spearman’s correlation analyses revealed that population of Lactobacillales was associated with lower Enterobacteriales, higher BW, and lower mortality of growing broilers. These results suggest that the modulation of ceca microbiota and the greatest productive parameters were achieved by supplementation of specific probiotic mixture. The selection of probiotics by their ability to drive cecal microbiota towards lactic acid bacteria colonization may be a strategic approach to improve the indicators of performance in broilers.