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Pre-Clinical Models pp 99–103Cite as

The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behavior

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1916))

Abstract

The open field test is used in studies of the neurobiological basis of anxiety and screening for novel drug targets and anxiolytic compounds. This test uses a camera to measure movement of the test animal in the peripheral and central zones of a 42 × 42 × 42 cm polyvinyl chloride box. This chapter describes a protocol for carrying out the open-field test for assessment of locomotion and anxiety-like behavior in mice.

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References

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Author information

Authors and Affiliations

  1. Laboratory of Psychiatric Neuroscience, Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD, Australia

    Ann-Katrin Kraeuter & Zoltán Sarnyai

  2. Discipline of Biomedicine, College of Public Health, Medicine and Veterinary Sciences, James Cook University, Townsville, QLD, Australia

    Ann-Katrin Kraeuter & Zoltán Sarnyai

  3. Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, SP, Brazil

    Paul C. Guest

Authors
  1. Ann-Katrin Kraeuter
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  2. Paul C. Guest
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  3. Zoltán Sarnyai
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Corresponding author

Correspondence to Zoltán Sarnyai .

Editor information

Editors and Affiliations

  1. Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

    Paul C. Guest

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Kraeuter, AK., Guest, P.C., Sarnyai, Z. (2019). The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behavior. In: Guest, P. (eds) Pre-Clinical Models. Methods in Molecular Biology, vol 1916. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-8994-2_9

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  • DOI: https://doi.org/10.1007/978-1-4939-8994-2_9

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-8993-5

  • Online ISBN: 978-1-4939-8994-2

  • eBook Packages: Springer Protocols

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