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Immunocytochemical mapping of the novel echinoderm neuropeptide SALMFamide 1 (S1) in the starfish Asterias rubens

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Abstract

The recent isolation and characterization of the SALMFamide neuropeptides S1 and S2 from the starfish Asterias rubens has initiated a series of studies on their distribution. Specific antisera have been raised against S1 and used in light-microscopical immunocytochemistry. The results of this study reveal for the first time a possible hyponeural innervation of the visceral musculature of the gut and the widespread neuronal distribution of S1, (i) in axons and cell bodies of both ectoneural and hyponeral regions of the radial nerve cord and circumoral nerve ring, (ii) in the nerve ring and nerve plexus of the tube feet, (iii) in the apical muscle, (iv) in skin, and (v) extensively throughout the digestive system. These discoveries are of particular interest in terms of the possible functional roles for S1 in Asterias rubens.

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Authors and Affiliations

  1. Department of Biology, Royal Holloway and Bedford New College, University of London, TW20 OEX, Egham, Surrey, UK

    Suzanna J. Moore & Michael C. Thorndyke

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  1. Suzanna J. Moore
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  2. Michael C. Thorndyke
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Part of this work has been previously reported as an abstract: (Moore et al.1990, 1991)

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Moore, S.J., Thorndyke, M.C. Immunocytochemical mapping of the novel echinoderm neuropeptide SALMFamide 1 (S1) in the starfish Asterias rubens . Cell Tissue Res 274, 605–618 (1993). https://doi.org/10.1007/BF00314559

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  • DOI: https://doi.org/10.1007/BF00314559

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