Skip to main content
Log in

The fish spleen: structure and function

  • Published:
Experientia Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. Abrahamsson, T., Holmgren, S., Nilsson, S. and Pettersson, K., Adrenergic and cholinergic effects on the heart, the lung and the spleen of the African lungfish,Protopterus aethiopicus. Acta physiol. scand.107 (1979) 141–147.

    Article  CAS  PubMed  Google Scholar 

  2. Abrahamsson, T., and Nilsson, S., Effects of nerve sectioning and drugs on the catecholamine content in the spleen of the cod,Gadus morhua. Comp. Biochem. Physiol.51C (1975) 231–233.

    Google Scholar 

  3. Agius, C., Phylogenetic development of melano-macrophage centres in fish. J. Zool., Lond.191 (1980) 11–31.

    Article  Google Scholar 

  4. Agius, C., and Roberts, R.J., Effects of starvation on the melanomacrophage centres of fish. J. Fish Biol.19 (1981) 161–169.

    Article  Google Scholar 

  5. Anderson, D.P., Roberson, B.S., and Dixon, O.W., Plaque-forming cells and humoral antibody in Rainbow trout (Salmo gairdneri) induced by immersion in aYersinia ruckeri O-antigen preparation. J. Fish. Res. Bd Can.36 (1979) 636–639.

    Article  Google Scholar 

  6. Arvy, L., Splénologie, 576 p. Gauthier-Villars, Paris 1965.

    Google Scholar 

  7. Balashov, N.V., Fänge, R., Govyrin, V.A., Leont'eva, G.R., Nilsson, S., and Prozorovskaya, M.P., On the adrenergic system of ganoid fish: the beluga,Huso huso (Chondrostei). Acta physiol. scand.111 (1981) 435–440.

    Article  CAS  PubMed  Google Scholar 

  8. Bonnet, V., De l'influence de l'hémorragie et de l'asphyxie sur le nombre des hématies dans le sang circulant des vertébrés inférieurs. J. Physiol. Path. gén.27 (1929) 735–740.

    Google Scholar 

  9. Catton, W.T., Blood cell formation in certain teleost fishes. Blood6 (1951) 39–60.

    Article  CAS  PubMed  Google Scholar 

  10. Chiller, J. M., Hodkins, H. O., Chambers, V.C., and Weiser, R.S., Antibody response in Rainbow trout (Salmo gairdneri) 1. Immunocompetent cells in the spleen and anterior kidney. J. Immun.102 (1969) 1193–1201.

    Article  CAS  PubMed  Google Scholar 

  11. Davies, B.N., and Withrington, P.G., The actions of drugs on the smooth muscle of the capsule and blood vessels of the spleen. Pharm. Rev.25 (1973) 373–414.

    CAS  PubMed  Google Scholar 

  12. Drâgotoiu-Untu, C., Sistemul reticulo-histocitar di splina deTinca. St. Si. cerc. Biol. Seria Zool. Bucuresti22 (1970) 337–340.

    Google Scholar 

  13. Drezewina, A., and Pettit, A., Sur les hyperplasies tissulaires consécutives a l'ablation de la rate chez les Ichthyopsidées. C.r. Soc. Biol. Paris56 (1904) 628–630.

    Google Scholar 

  14. Dustin, P., Recherches sur les organes hématopoiétiques duProtopterus Dolloi. Archs Biol.45 (1934) 1–26.

    Google Scholar 

  15. Dustin, P., Les housses spléniques de Schweigger-Seidel. Etude d'histologie et d'histophysiologie comparées. Archs Biol.49 (1939) 1–99.

    Google Scholar 

  16. Ellis, A.E., Antigen-trapping in the spleen and kidney of the plaicePleuronectes platessa. L., J. Fish. Dis.3 (1980) 413–426.

    Article  Google Scholar 

  17. Etlinger, H.M., Hodgins, H.O., and Chiller, J.M., Evolution of the lymphoid system. I. Evidence for lymphocyte heterogeneity in Rainbow trout revealed by the organ distribution of mitogenic responses. J. Immun.116 (1976) 1547–1553.

    Article  CAS  PubMed  Google Scholar 

  18. Fänge, R., A comparative study of lymphomyeloid tissue in fish. Dev. comp. Immun.6, suppl. 2 (1982) 23–33.

    Google Scholar 

  19. Fänge, R., and Johansson-Sjöbeck, M.-L., The effect of splenectomy on the hematology and on the activity of δ-aminolevulinic acid dehydratase (ALA-D) in hemopoietic tissues of the dogfish,Scyliorhinus canicula (Elasmobrachii). Comp. Biochem. Physiol.52A (1975) 577–580.

    Article  Google Scholar 

  20. Fänge, R., and Mattisson, A., The lymphomyeloid (hemopoietic) system of the Atlantic nurse shark,Ginglymostoma cirratum. Biol. Bull.160 (1981) 240–249.

    Article  Google Scholar 

  21. Fänge, R., and Pulsford, A., Structural studies on lymphomyeloid tissues of the dogfish,Scyliorhinus canicula L. Cell Tiss. Res.230 (1982) 337–351.

    Google Scholar 

  22. Fänge, R., and Sundell, G., Lymphomyeloid tissues, blood cells and plasma proteins inChimaera monstrosa (Pisces, Holocephali). Acta zool., Stockh.50 (1969). 155–168.

    Article  Google Scholar 

  23. Ferguson, H.W., The relationship between ellipsoids and melanomacrophage centres in the spleen of turbot (Scophthalmus maximus). J. comp. Path.86 (1976) 377–380.

    Article  CAS  PubMed  Google Scholar 

  24. Ferren, F.A., Role of the spleen in the immune response of teleosts and elasmobranchs. J. Florida med. Ass.54 (1967) 434–437.

    PubMed  Google Scholar 

  25. Fey, F., Hamatologische Untersuchungen der blubildenden Gewebe niederer Wirbeltiere. Folia haemat.84 (1965) 122–146.

    CAS  Google Scholar 

  26. Finstad, J., and Good, R.A., Phylogenetic studies of adaptive immune response in the lower vertebrates, in: Phylogeny of Immunity, pp. 173–189. Eds R.T. Smith, P.A. Miescher and R.A. Good. Univ. Florida Press, Gainesville 1966.

    Google Scholar 

  27. Fujii, T., Electron microscopy of the lencocytes of the typhlosome in ammocoetes, with special attention to the antibody-producing cells. J. Morph.173 (1981) 87–100.

    Article  Google Scholar 

  28. Haider, G., Beitrag zur Kenntnis der mikroskopischen Anatomie der Milz einiger Teleostier. Zool. Anz.177 (1966) 348–367.

    Google Scholar 

  29. Hevesy, G., Lockner, D., and Sletten, K., Iron metabolism and erythrocyte formation in fish. Acta physiol. scand.60 (1964) 256–266.

    Article  CAS  PubMed  Google Scholar 

  30. Holmgren, S., Sympathetic innervation of the coeliac artery from a teleost,Gadus morhua. Comp. Biochem. Physiol.60C (1978) 27–32.

    Google Scholar 

  31. Holmgren, S., and Nilsson, S., Drug effects on isolated artery strips from two teleosts,Gadus morhua andSalmo gairdneri. Acta physiol. scand.90 (1974) 431–437.

    Article  CAS  PubMed  Google Scholar 

  32. Holmgren, S., and Nilsson, S., Effect of some adrenergic and cholinergic drugs on isolated spleen strips from the cod,Gadus morhua. Eur. J. Pharmac.32 (1975) 163–169.

    Article  CAS  Google Scholar 

  33. Holmgren, S., and Nilsson, S., Effects of denervation, 6-hydroxy-dopamine and reserpine on the cholinergic and adrenergic responses of the spleen of the cod,Gadus morhua. Eur. J. Pharmac.39 (1976) 53–59.

    Article  CAS  Google Scholar 

  34. Holmgren, S., and Nilsson, S., Neuropharmacology of adrenergic neurons in teleost fish. Comp. Biochem. Physiol.72C (1982) 289–302.

    CAS  Google Scholar 

  35. Johansson-Sjöbeck, M.-L., The effects of splenectomy on the hematology and on the activity of delta-aminolevulinic acid dehydratase (ALA-D) in hematopoietic tissues of the European eel,Anguilla anguilla. Comp. Biochem. Physiol.63A (1979) 333–338.

    Article  Google Scholar 

  36. Jordan, H.E., The evolution of blood-forming tissues. Q. Rev. Biol.8 (1933) 645–655.

    Article  Google Scholar 

  37. Jordan, H.E., and Speidel, C.C., Blood formation in the African lungfish, under normal conditions and under conditions of prolonged activation and recovery. J. Morph.51 (1931) 319–371.

    Article  Google Scholar 

  38. Kanesada, A., A phylogenetical survey of hemocytopoietic tissues in submammalian vertebrates. Bull. Yamaguchi med. School4 (1956) 1–22.

    Google Scholar 

  39. Knisely, M.H., I. Microscopic observations of the circulatory system of living unstimulated spleens. Anat. Rec.65 (1936) 131–148.

    Article  Google Scholar 

  40. Lobb, C.J., and Clem, L.W., Fish lymphocytes differ in the expression of surface immunoglobulin. Dev. comp. Immun.6 (1982) 473–479.

    Article  CAS  Google Scholar 

  41. Maas, M.G., and Bootsma, R., Uptake of bacterial antigens in the spleen. Dev. comp. Immun., suppl.2 (1982) 47–52.

    Google Scholar 

  42. MacKenzie, D.W., Whipple, A.O., and Wintersteiner, M.P., Studies on the microscopic anatomy and physiology of living transilluminated mammalian spleens. Am. J. Anat.68 (1941) 397–456.

    Article  Google Scholar 

  43. Matthews, L.H., and Parker H.W., Note on the anatomy and biology of the basking shark (Cetorhinus maximus). Proc. zool. Soc. Lond.120 (1950) 535–576.

    Article  Google Scholar 

  44. Mattisson, A., and Fänge, R., The cellular structure of the Leydig organ in the shark,Etmopterus spinax (L.). Biol. Bull.162 (1982) 182–194.

    Article  Google Scholar 

  45. Miescher-Ruesch, F., Über das Leben des Rhein-Lachses in Süsswasser. I. Abhandlung: Die Milz des Rhein-Lachses und ihre Veränderungen. Arch. Anat. Physiol. (Anat. Abt.), (1881) 193–218.

  46. Millot, J., Nathony, J., and Robineau, D., Anatomie de laLatimeria chalumae, tome III, pp. 133–134. Ed. Centre national de la Recherche scientifique, Paris 1978.

  47. Mislin, H., Der Phasenweschsel des Rheinlachses (Salmo salar L.) unter besonderer Berücksichtigung des Ernährungsapparates. Revue suisse Zool., suppl.48 (1941) 1–181.

    Google Scholar 

  48. Morrow, W.J.W., Harris, J.E., and Pulsford, A., Immunological responses of the dogfish (Scyliorhinus canicula L.). Acta zool., Stockh.63 (1982) 153–159.

    Article  Google Scholar 

  49. Murata, H., Comparative studies of the spleen in submammalian vertebrates I. Topographical anatomy and relative weight of the spleen. Okajimas Folia anat. jap.33 (1959a) 1–9.

    Article  Google Scholar 

  50. Murata, H., Comparative studies of the spleen in submammalian vertebrates II. Minute structure of the spleen with special reference to the periarterial lymphoid sheath. Bull. Yamaguchi med. School6 (1959b) 83–105.

    Google Scholar 

  51. Neale, N.L., and Chavin, W., Lymphocytic tissue alterations during the primary immune response of the goldfish (Carassius auratus L.). Michigan Academician3 (1971) 23–30.

    Google Scholar 

  52. Nilsson, S., On the adrenergic system of ganoid fish: the Florida spotted gar,Lepisosteus platyrhincus (Holostei). Acta physiol. scand.111 (1981) 447–454.

    Article  CAS  PubMed  Google Scholar 

  53. Nilsson, S., Autonomic nerve function in the vertebrates, 253 p. Springer Verlag, Berlin/Heidelberg/New York 1983.

    Book  Google Scholar 

  54. Nilsson, S., and Grove, D.J., Adrenergic and cholinergic innervation of the spleen of the cod,Gadus morhua. Eur. J. Pharmac.28 (1974) 135–143.

    Article  CAS  Google Scholar 

  55. Nilsson, S., and Holmgren, S., Uptake and release of catecholamines in sympathetic nerve fibres in the spleen of the cod,Gadus morhua. Eur. J. Pharmac.39 (1976) 41–51.

    Article  CAS  Google Scholar 

  56. Nilsson, S., Holmgren, S., and Grove, D.J., Effects of drugs and nerve stimulation on the spleen and arteries of two species of dogfish,Scyliorhinus canicula andSqualus acanthias. Acta physiol. scand.95 (1975) 219–230.

    Article  CAS  PubMed  Google Scholar 

  57. Opdyke, D.F., and Opdyke, N.E., Splenic responses to stimulation inSqualus acanthias. Am. J. Physiol.221 (1971) 623–625.

    Article  CAS  PubMed  Google Scholar 

  58. Ortiz-Muniz, G., and Sigel, M.M., Antibody synthesis in lymphoid organs of two marine teleosts. J. reticuloendoth. Soc.9 (1971) 42–52.

    CAS  Google Scholar 

  59. Pulsford, A., Fänge, R., and Morrow, W.J.W., Cell types and interactions in the spleen of the dogfishScyliorhinus canicula L.; an electron microscopic study. J. Fish Biol.21 (1982) 649–662.

    Article  Google Scholar 

  60. Rafn, S., and Wingstrand, K.G., Structure of intestine, pancreas and spleen of the Australian lungfish,Neoceratodus forsteri. Zool. Scripta10 (1981) 223–239.

    Article  Google Scholar 

  61. Reite, O.B., The evolution of vascular smooth muscle responses to histamine and 5-hydroxytryptamine. I. Occurrence of stimulatory actions in fish. Acta physiol. scand.75 (1969) 221–239.

    Article  CAS  PubMed  Google Scholar 

  62. Sailendri, K., and Mhukkaruppan, V.R., The immune response of the teleostTilapia mossambica to soluble and cellular antigen. J. exp. Zool.191 (1975) 271–382.

    Article  Google Scholar 

  63. Schmidt-Nielsen, S., and Schmidt-Nielsen, K., Grösse und Eisengehalt der Milz der Forelle. Norske Vidensk Selsk Forh (Norway)12 (1939) 63–66.

    Google Scholar 

  64. Schweigger-Seidel, F., Untersuchungen über die Milz. Virchow's Arch.27 (1863) 460–504.

    Article  Google Scholar 

  65. Smith, A.M., Potter, M., and Merchant, E.B., Antibody-forming cells in the pronephros of the teleostLepomis macrochirus. J. Immun.99 (1967) 876–882.

    Article  CAS  PubMed  Google Scholar 

  66. Tait, J., A review of the structure and function of the spleen. Br. med. J.2 (1927) 291–294.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  67. Tanaka, Y., Saito, Y., and Gotoh, H., Vascular architecture and intestinal hematopoietic nests of two cyclostomes,Eptatretus burgeri and ammocoetes ofEntosphenus reissneri. J. Morph.170 (1981) 71–93.

    Article  CAS  PubMed  Google Scholar 

  68. Tischendorf, F., Die Milz, in: Handbuch der mikroskopischen Anatomie des Menschen. vol. 6/6, pp. 1–968. Eds W.V. Möllendorf and W. Bargmann. Springer-Verlag, Berlin/Heidelberg/New York 1969.

    Google Scholar 

  69. Vairel, J., Action de l'adrénaline et de l'acetylcholine sur la rate. J. Physiol. Path. gén.31 (1933) 42–52.

    CAS  Google Scholar 

  70. Wahlqvist, I., and Nilsson, S., Sympathetic nervous control of the vasculature in the tail of the Atlantic cod,Gadus morhua. J. comp. Physiol.144 (1981) 153–156.

    Article  CAS  Google Scholar 

  71. Walvig, F., Blood and parenchymal cells in the spleen of the icefishChaenocephalus aceratus (Lönnberg). Nytt Magasin Zool. (Norway)6 (1958) 111–120.

    Google Scholar 

  72. White, R.G., Antigen transport in the spleen. Immun. today2 (1981) 150–151.

    Article  CAS  PubMed  Google Scholar 

  73. Winberg, M., Holmgren, S., and Nilsson, S., Effects of denervation and 6-hydroxydopamine on the activity of choline acetyltransferase in the spleen of the cod,Gadus morhua. Comp. Biochem. Physiol.69C (1981) 141–143.

    CAS  Google Scholar 

  74. Yamamoto, K.I., Itazawa, Y., and Kobayashi, H., Supply of erythrocytes into the circulating blood from the spleen of exercised fish. Comp. Biochem. Physiol.65A (1980) 5–11.

    Google Scholar 

  75. Yamamoto, K., Itazawa, Y., and Kobayashi, H., Erythrocyte supply from the spleen and hemoconcentration in hypoxic yellowtail. Marine Biol.73 (1983) 221–226.

    Article  Google Scholar 

  76. Yoffey, J.M., A contribution to the study of the comparative histology and physiology of the spleen, with reference chiefly to its cellular constituents. I. In fishes. J. Anat.63 (1929) 314–344.

    CAS  PubMed  PubMed Central  Google Scholar 

  77. Yu, M.-L., Sarot, D.A., Filazzola, R.J., and Perlmutter, A., Effects on splenectomy on the immune response of the Blue gouramiTrichogaster trichopterus, to infectious pancreatic necrosis (IPN) virus. Life Sci.9 part II (1970) 749–755.

    Article  CAS  Google Scholar 

  78. Zapata, A., Splenic erythropoiesis and thrombopoiesis in elasmobranchs. An ultrastructural study. Acta zool., Stockh.61 (1980) 59–64.

    Article  Google Scholar 

  79. Zapata, A., Lymphoid organs of teleost fish. III. Splenic lymphoid tissue ofRutilus rutilus andGobio gobio. Dev. comp. Immun.6 (1982) 87–94.

    Article  CAS  Google Scholar 

  80. Zwillenberg, H.H.L., Bau und Funktion der Forellenmilz. Hans Huber, Bern/Stuttgart 1964.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fänge, R., Nilsson, S. The fish spleen: structure and function. Experientia 41, 152–158 (1985). https://doi.org/10.1007/BF02002607

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02002607

Key words

Navigation