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On the validity of the steady state assumption of enzyme kinetics

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Abstract

By estimating relevant time scales, a simple new condition can be found that ensures the validity of the steady state assumption for a standard enzyme-substrate reaction. The generality of the approach is demonstrated by applying it to the determination of validity criteria for the steady state assumption applied to an enzyme-substrate-inhibitor system.

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  1. Department of Applied Mathematics and Computer Science, The Weizmann Institute of Science, IL-76100, Rehovot, Israel

    Lee A. Segel

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  1. Lee A. Segel
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Segel, L.A. On the validity of the steady state assumption of enzyme kinetics. Bltn Mathcal Biology 50, 579–593 (1988). https://doi.org/10.1007/BF02460092

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  • DOI: https://doi.org/10.1007/BF02460092

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