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Evolution of interictal activity in models of mesial temporal lobe epilepsy
2023, Neurobiology of DiseaseGABA<inf>B</inf> receptor outward currents are transiently disclosed by the convulsant 4-aminopyridine in vitro
2023, Current Research in NeurobiologyHuman induced pluripotent stem cell (hiPSC)-derived neurons respond to convulsant drugs when co-cultured with hiPSC-derived astrocytes
2017, ToxicologyCitation Excerpt :The balance between the excitatory and inhibitory signals must be precisely controlled to maintain normal functions in the brain. Several convulsant drugs cause the dominant excitatory signals by direct and/or indirect effects, and induce the seizure-like discharge in neurons (Juhng et al., 1999; Lothman and Collins, 1981; Sokal et al., 2000; Voskuyl and Albus, 1985). This seizure-like discharge synchronizes among neurons and forms a hypersynchronous burst that is considered to be a main trigger of seizure.
A brain slice experimental model to study the generation and the propagation of focally-induced epileptiform activity
2016, Journal of Neuroscience Methods
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