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Toxicological index of paraquat: A new strategy for assessment of severity of paraquat poisoning in 128 patients

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Abstract

A new assessment of the severity of paraquat poisoning in 128 patients has been developed. It involves toxicological index of paraquat and discriminant function score. This system not only allows a more accurate assessment of severity of the poisoning, but also provides a more reliable prediction of the outcome in an early stage for the purpose of forensic and clinical toxicology.

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    The best cutoff value for hypokalemia is the serum potassium level of 3.6 mEq/L, with a sensitivity of 75% and a specificity of 54%. Although many studies regarding prognostic indicators of survivor in patients poisoned with PQ using plasma/urine PQ concentration have been attempted, the prediction based on clinical parameters is the easiest available method and it is possible to rapidly update assessment should a patient’s condition deteriorate.4–14 In the present study, we developed a predictive method about the outcome of PQ poisoning by using clinical parameters, which are readily available in the ED environment.

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