Morphological evidence that CA1 hippocampal afferents monosynaptically innervate PV-containing neurons and NADPH-diaphorase reactive cells in the medial prefrontal cortex (Areas 25/32) of the rat

doi:10.1016/S0006-8993(02)02487-3

Brain Research

Volume 946, Issue 2, 16 August 2002, Pages 314-322

https://doi.org/10.1016/S0006-8993(02)02487-3 Get rights and content

Abstract

Immunocytochemical and ultrastructural evidence is presented indicating that direct inputs from the hippocampal CA1 field to prelimbic (area 32) and infralimbic (area 25) cortices in the rat, innervate not only ‘spiny’ (presumed pyramidal) neurons but also monosynaptically contact NADPH-diaphorase reactive cells and parvalbumin-containing local circuit neurons—the latter cell type is shown to be GABA immunoreactive. Similar evidence of direct CA1 input to local circuit neurons containing either calbindin or calretinin was not found.

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Acknowledgements

This work was funded by The Wellcome Trust, Beit Memorial Research Fund and The Royal Society. Paul Gabbott undertook this research as a Wellcome Trust Research Career Development Fellow.

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Short communicationMorphological evidence that CA1 hippocampal afferents monosynaptically innervate PV-containing neurons and NADPH-diaphorase reactive cells in the medial prefrontal cortex (Areas 25/32) of the rat

Abstract

Section snippets

Acknowledgements

Brain Res.

Brain Res.

Brain Res.

Brain Res.

Trends Neurosci.

Brain Res.

Brain Res.

Neuroscience

Brain Res.

Brain Res.

Experimental Neuroanatomy

Hippocampal afferents to the rat prefrontal cortex: synaptic targets and relation to dopamine terminals

J. Comp. Neurol.

Hippocampal, subicular, and entorhinal afferents and synaptic integration in rodent cingulate cortex

Local circuit neurons in the medial prefrontal cortex (areas 24a,b,c, 25 and 32) in the monkey: I. Cell morphology and morphometrics

J. Comp. Neurol.

Local-Circuit neurons in the Medial Prefrontal Cortex (Areas 25, 32, 24b) in the Rat: Morphology and Quantitative Distribution

J. Comp. Neurol.

Axo-somatic and axo-dendritic synapses of the cerebral cortex: an electron microscope study

J. Anat.

Topographic projections from the subiculum to the limbic regions of the medial frontal cortex in the cat

Neurosci. Lett.

Enthorhinal cortex of the rat cytoarchitecture subdivisions and the origin and distribution of cortical efferents

Hippocampus

Mouse hippocampo-prefrontal paired-pulse facilitation and long-term potentiation in vivo

Neuroreport

Excitatory amino acid pathway from the hippocampus to the prefrontal cortex: contribution of AMPA receptors in hippocampo-prefrontal cortex transmission

Eur. J. Neurosci.

Short communication
Morphological evidence that CA1 hippocampal afferents monosynaptically innervate PV-containing neurons and NADPH-diaphorase reactive cells in the medial prefrontal cortex (Areas 25/32) of the rat