In vitro fatigue of human tendons
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2022, Journal of the Mechanical Behavior of Biomedical MaterialsCitation Excerpt :Fatigue strengths are frequently used to determine safe loading limits for specific materials, designs, and loading configurations (Budynas and Nisbett, 2014), and the relationship between fatigue strength and cycles to failure (S-N curve) has been experimentally characterized for most standard metals (Fatemi, 2000), plastics (McKeen, 2009), and composites (Harris, 2003) by applying thousands to millions of loading cycles (high-cycle testing) to sectioned specimen coupons that are representative of the bulk material. In biological materials, fatigue strengths are largely unknown, with only a few studies developing S-N curves for soft fibrous tissues (Sadeghi et al., 2017; Schechtman and Bader, 1997; Scholze et al., 2018). Fatigue studies in soft and hard tissue are typically conducted at randomized stress levels; however, international test standards recommend the fatigue testing of multiple specimens at targeted stress levels (ASTM, 2017).
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Current address: Departamento de Estudos em Ciencia e Tecnologica, Centro de Informacao Cientifica e Tecnologica, FIOCRUZ-Fundacao Oswaldo Cruz, Brazil.