Current Biology
Volume 8, Issue 19, 24 September 1998, Pages R687-R689
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Size control: Cell proliferation does not equal growth

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Abstract

Division subdivides mass without increasing it. So one should not expect that an increase in cell division would make an organism bigger. Both classic and recent experiments confirm this simple rationale: altering proliferation produces normally sized body structures with either especially small or exceptionally large cells.

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TT Su and PH O’Farrell, Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California 94143-0448, USA.

Present address for TT Su: MCD Biology, University of Colorado, Boulder, Colorado 80309, USA.

E-mail address for TT Su: [email protected].

E-mail address for PH O’Farrell: [email protected].