The endoplasmic reticulum Ca2+ store: a view from the lumen

doi:10.1016/S0968-0004(97)01143-2

Trends in Biochemical Sciences

Volume 23, Issue 1, January 1998, Pages 10-14

https://doi.org/10.1016/S0968-0004(97)01143-2 Get rights and content

Abstract

The endoplasmic reticulum (ER) and its specialized subcompartments such as the sarcoplasmic reticulum, is the main dynamic Ca²⁺ storage compartment of the cell. Key cellular functions are regulated, either directly or indirectly, by the free Ca²⁺ concentration in the ER. This article discusses the properties of Ca²⁺ storage in the ER and considers the functions that appear to be regulated by the Ca²⁺ stores within the ER, both in and around the ER and at a distance from it.

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Talking pointThe endoplasmic reticulum Ca2+ store: a view from the lumen

Abstract

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The endoplasmic reticulum Ca²⁺ store: a view from the lumen