Biochimica et Biophysica Acta (BBA) - Bioenergetics
Volume 1837, Issue 10, October 2014, Pages 1781-1789
Cytotoxicity of mitochondria-targeted resveratrol derivatives: Interactions with respiratory chain complexes and ATP synthase
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Abbreviations
B-CLL
B-cell chronic lymphocytic leukemia
BSA
bovine serum albumin
BTPI
4-triphenylphosphoniumbutyl
CoQ
coenzyme Q
CsA
cyclosporin A
DCPI
2,6-dichlorophenolindophenol
Δψm
mitochondrial membrane potential
DMEM
Dulbecco's Modified Eagle Medium
Δμ̃H
proton electrochemical gradient
ECAR
extracellular acidification rate
FACS
fluorescence-activated cell scanner
FBS
fetal bovine serum
FCCP
carbonyl cyanide p-trifluoromethoxy-phenylhydrazone
HBSS
Hank's Balanced Salt Solution
H2DCF-DA
2′,7′-dichlorodihydrofluorescein-diacetate
IMM
inner mitochondrial membrane
LDH
lactate dehydrogenase
MPT
mitochondrial permeability transition
OCR
oxygen consumption rate
OL
oligomycin
PEG-SOD
polyethyleneglycol-superoxide dismutase
PEG-CAT
polyethyleneglycol-catalase
PEP
phosphoenolpyruvate
PK
pyruvate kinase
R-4′BTPI
4′-(4-triphenylphosphoniumbutyl) resveratrol iodide
R-3BTPI
3-(4-triphenylphosphoniumbutyl) resveratrol iodide
RDA-4′BTPI
3,5-diacetyl-4′-(4-triphenylphosphoniumbutyl) resveratrol iodide
RDA-3BTPI
4′,5-diacetyl-3-(4-triphenylphosphoniumbutyl) resveratrol iodide
RDM-4′BTPI
3,5-dimethyl-4′-(4-triphenylphosphoniumbutyl) resveratrol iodide
RDM-3BTPI
4′,5-dimethyl-3-(4-triphenylphosphoniumbutyl) resveratrol iodide
RLM
rat liver mitochondria
ROI
regions of interest
ROS
reactive oxygen species
MTT
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
Keywords
Resveratrol
Triphenylphosphonium
ROS
Mitochondria
Respiratory chain
ATP synthase
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