Cell
Volume 142, Issue 6, 17 September 2010, Pages 889-901
ArticleMembrane Remodeling Induced by the Dynamin-Related Protein Drp1 Stimulates Bax Oligomerization
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Graphical Abstract
Highlights
► Drp1 promotes tBid-induced Bax oligomerization by triggering membrane hemifusion ► Drp1 induces membrane hemifusion independently of its GTPase activity ► Cardiolipin is essential for Drp1-induced membrane hemifusion ► Drp1 mutants lacking membrane hemifusion activity delay Bax oligomerization in vivo
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These authors contributed equally to this work
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Present address: MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK
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