Cell
Volume 155, Issue 5, 21 November 2013, Pages 990-996
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Divergent Transcription: A Driving Force for New Gene Origination?

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The mammalian genome is extensively transcribed, a large fraction of which is divergent transcription from promoters and enhancers that is tightly coupled with active gene transcription. Here, we propose that divergent transcription may shape the evolution of the genome by new gene origination.

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