Gene regulation in the immediate-early response process
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Keywords
Immediate-early response
Signaling cascades
Poised genes
Transcription factors
Enhancers
Abbreviations
IER
immediate-early response
IEG
immediate-early gene
PRG
primary response gene
SRG
secondary response genes
PDGF
platelet-derived growth factor
EGF
epidermal growth factor
SRF
serum-response factor
NF-kB
nuclear factor-kB
CREB
cyclic AMP response element-binding protein
AP-1
activator protein-1
TCF
ternary complex factor
ERK
extracellular signal-regulated kinase
MAPK
Mitogen-activated protein kinases
ELK1
E26-like kinase
MRTF
myocardin related transcription factor
NF1
nuclear factor 1
PARP1
Poly (ADP-ribose) polymerase 1
RSK
p90 ribosomal S6 kinase
JNK
c-Jun N- terminal kinase
ERK5
extracellular signal regulated kinase-5
BMK1
Big MAP kinase-1
MSK
Mitogen/stress activated protein kinase
RNA Pol II
RNA polymerase II
GO
Gene Ontology
TBP
TATA binding protein
TSS
Transcription Start Site
HAT
histone acetyl transferase
IRF3
interferon regulatory factor 3
TLR
Toll-like receptor
NGF
nerve growth factor
G protein
guanine nucleotide binding protein
TF
Transcription Factor
MKL
megakaryoblastic leukemia
ESC
embryonic stem cells
DSIF
DRB sensitivity-inducing factor
NELF
negative elongation factor
P-TEFb
positive transcription elongation factor
CTD
C-terminal domain
eRNA
enhancer RNA
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© 2016 The Authors. Published by Elsevier Ltd.