Molecular Cell
Volume 73, Issue 2, 17 January 2019, Pages 264-277.e5
ArticleType III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity
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Graphical Abstract
Keywords
cryo-EM
type III-A CRISPR-Cas complexes
T. onnurineus Csm
ternary complex assembly with crRNA and target RNA
5′ repeat tag pairing controls autoimmunity
RNA cleavage with 6-nt periodicity
DNase activity regulation by Glu residues
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