Neuron
Volume 75, Issue 3, 9 August 2012, Pages 402-409
ReportFunctional Significance of Isoform Diversification in the Protocadherin Gamma Gene Cluster
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Highlights
► Mice lacking the three C-type Pcdhg isoforms phenocopy mice lacking all 22 isoforms ► Indistinguishable cellular and synaptic changes resulting from neuronal apoptosis ► Bax deficiency rescues the lethality of C-type knockouts but not that of null mutants ► Mice lacking three A-type Pcdhg isoforms are phenotypically normal
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Present address: Department of Physiology, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA
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Present address: Department of Bioinformatics and Computational Biology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA
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