Neuron
Volume 109, Issue 8, 21 April 2021, Pages 1283-1301.e6
ArticleTrem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
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Graphical abstract
Keywords
Alzheimer’s disease
TREM2
microglia
tauopathy
neurodegeneration
gliosis
neuroinflammation
single-cell RNA sequencing
MRI
disease-associated microglia
Cited by (0)
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Present address: Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
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Present address: Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA
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These authors contributed equally
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