Short communicationSignal peptide cleavage from GP3 enabled by removal of adjacent glycosylation sites does not impair replication of equine arteritis virus in cell culture, but the hydrophobic C-terminus is essential
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Acknowledgements
Funding was provided by the EU (FP7, Initial Training network “Virus entry”). We thank Eric Snijder (Virology, University of Leiden) for the provision of the cDNA clone of EAV and for anti-E antibodies, Peter Rottier (Virology, University of Utrecht) for supplying anti-GP3 antibodies, Udeni Balasuriya (Gluck Equine Research Center, University of Kentucky) for anti-GP2 antiserum and Bastian Thaa for reading of the manuscript.
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