Growth of the developing mouse heart: An interactive qualitative and quantitative 3D atlas
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Highlights
► We present mouse heart development from first onset till late gestation. ► Interactive 3D reconstructions show heart morphology and proliferation patterns. ► Tube formation, tube elongation and early chamber formation overlap in time. ► Fast proliferation only occurs in splanchnic mesoderm and forming chambers. ► Proliferation rate is highest at the trabecular base and tapers off with distance.
Keywords
Cardiac development
Developmental biology
Quantitative reconstructions
Proliferation
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These authors contributed equally.
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