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Axial Period of Fibrinogen and Fibrin

Abstract

X-RAY diffraction was first applied to the analysis of blood clotting by Bailey, Astbury and Rudall1. The apparent persistence of the α-type wide-angle X-ray diagram when fibrinogen is converted to fibrin led these investigators to conclude that “fibrinogen is no other than an insoluble modification of fibrin without any fundamental change in molecular plan”.

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STRYER, L., COHEN, C. & LANGRIDGE, R. Axial Period of Fibrinogen and Fibrin. Nature 197, 793–794 (1963). https://doi.org/10.1038/197793a0

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