Abstract
MANY physiological and behavioural variables in adult life have been related to infantile experience. There have, however, been no large scale studies of the effects of infantile stimulation on the immunological system—influences on which might have important implications in host resistance to infectious disease, to cancer (in view of growing evidence that resistance to many tumours is immunological in nature1,2) and possibly to auto-immune diseases, which may have an association with states of immunological insufficiency3. Emotions and stress have been related to the onset and course of infections, cancer and auto-immune diseases4, and we have now studied differential immunological responses to flagellin in rats handled and not handled before weaning.
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SOLOMON, G., LEVINE, S. & KRAFT, J. Early Experience and Immunity. Nature 220, 821–822 (1968). https://doi.org/10.1038/220821a0
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DOI: https://doi.org/10.1038/220821a0
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