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Stochastic Model for Abnormal Clone Spread through Epithelial Basal Layer

Abstract

The induction of a tumour in the basal layer of an epithelium has been simulated by computer. The primary assumption is that tumour growth begins when a single abnormal cell divides faster than surrounding normal cells by a factor K, the “carcinogenic advantage”.

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WILLIAMS, T., BJERKNES, R. Stochastic Model for Abnormal Clone Spread through Epithelial Basal Layer. Nature 236, 19–21 (1972). https://doi.org/10.1038/236019a0

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