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Non-genetic individuality: chance in the single cell

Nature volume 262, pages 467–471 (1976)Cite this article

Abstract

The individuality of bacterial cells grown in homogeneous conditions was demonstrated by showing characteristic behavioural differences which persist over their lifespans. Poissonian fluctuation of small numbers of generator molecules can explain this individuality and may apply to such processes as differentiation and asynchrony of cultures.

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Authors and Affiliations

  1. Department of Biochemistry, University of California, Berkeley, California, 94720

    John L. Spudich & D. E. Koshland Jr

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  1. John L. Spudich
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  2. D. E. Koshland Jr
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Spudich, J., Koshland, D. Non-genetic individuality: chance in the single cell. Nature 262, 467–471 (1976). https://doi.org/10.1038/262467a0

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