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β-Chain contact sites in the haemoglobin S polymer

Abstract

The amino acid residues involved in the areas of contact that stabilise the haemoglobin S polymer fibre seem to be the same ones that stabilise the basic unit of the deoxyhaemoglobin S crystal: the Wishner–Love double strand. The haemoglobin S fibre is probably formed by a unique packing of these double strands.

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Nagel, R., Johnson, J., Bookchin, R. et al. β-Chain contact sites in the haemoglobin S polymer. Nature 283, 832–834 (1980). https://doi.org/10.1038/283832a0

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