Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Developmental biology

One cell, two fates

Nature volume 408, pages 43–45 (2000)Cite this article

The two types of cell that make up blood vessels can develop from the same precursor. This discovery might improve our understanding of the role of blood vessels in disorders ranging from cancer to heart disease.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: A common origin for the two types of blood-vessel cell.

References

  1. Yamashita, J. et al. Nature 408, 92–96 (2000).

    Article  ADS  CAS  Google Scholar 

  2. Carmeliet, P. & Jain, R. K. Nature 407, 249–257 (2000).

    Article  CAS  Google Scholar 

  3. Carmeliet, P. Nature Med. 6, 389–395 ( 2000).

    Article  CAS  Google Scholar 

  4. Rafii, S. J. Clin. Invest. 105, 17–19 (2000).

    Article  CAS  Google Scholar 

  5. Isner, J. M. & Asahara, T. J. Clin. Invest. 103 , 1231–1236 (1999).

    Article  CAS  Google Scholar 

  6. Gittenberger-de Groot, A. C., DeRuiter, M. C., Bergwerff, M. & Poelmann, R. E. Arterioscler. Thromb. Vasc. Biol. 19, 1589– 1594 (1999).

    Article  CAS  Google Scholar 

  7. Nakajima, Y., Mironov, V., Yamagishi, T., Nakamura, H. & Markwald, R. R. Dev. Dyn. 209, 296–309 (1997).

    Article  CAS  Google Scholar 

  8. Hellstrom, M. et al. Development 126, 3047– 3055 (1999).

    CAS  PubMed  Google Scholar 

  9. Hirschi, K. K., Rohovsky, S. A. & D'Amore, P. A. J. Cell Biol. 141, 805– 814 (1998).

    Article  CAS  Google Scholar 

  10. Campbell, J. H., Efendy, J. L., Han, C. L., Girjes, A. A. & Campbell, G. R. J. Vasc. Res. 37 , 364–371 (2000).

    Article  CAS  Google Scholar 

  11. Carmeliet, P. et al. Nature 380, 435–439 (1996).

    Article  ADS  CAS  Google Scholar 

  12. Shalaby, F. et al. Cell 89, 981–990 (1997).

    Article  CAS  Google Scholar 

  13. Lindahl, P., Hellstrom, M., Kalen, M. & Betsholtz, C. Curr. Opin. Lipidol. 9, 407–411 ( 1998).

    Article  CAS  Google Scholar 

  14. Eisenberg, L. M. & Markwald, R. R. Circ. Res. 77, 1–6 (1995 ).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Center for Transgene Technology and Gene Therapy, Katholieke Universiteit Leuven, Campus Gasthuisberg, Herestraat 49, Leuven, B-3000, Belgium

    Peter Carmeliet

Authors
  1. Peter Carmeliet
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Peter Carmeliet.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Carmeliet, P. One cell, two fates. Nature 408, 43–45 (2000). https://doi.org/10.1038/35040684

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/35040684

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing