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BLUEPRINT to decode the epigenetic signature written in blood

Nature Biotechnology volume 30, pages 224–226 (2012)Cite this article

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To the Editor:

Last October, scientists gathered in Amsterdam to celebrate the start of BLUEPRINT (http://www.blueprint-epigenome.eu/), an EU-funded consortium that will generate epigenomic maps of at least 100 different blood cell types. With this initiative, Europe has pledged a substantial contribution to the ultimate goal of the International Human Epigenome Consortium (IHEC) to map 1,000 human epigenomes. Here, we provide a brief background to the scientific questions that prompted the formation of BLUEPRINT, summarize the overall goals of BLUEPRINT and detail the specific areas in which the consortium will focus its initial efforts and resources.

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Author information

Authors and Affiliations

  1. Wellcome Trust Sanger Institute, Hinxton, UK

    David Adams, Nicole Soranzo & Michael Stratton

  2. Second University of Naples, Naples, Italy

    Lucia Altucci

  3. Universite De Geneve, Geneva, Switzerland

    Stylianos E Antonarakis & Emmanouil T Dermitzakis

  4. Vivia Biotech, Madrid, Spain

    Juan Ballesteros

  5. University College London, London, UK

    Stephan Beck & Tariq Enver

  6. University of Edinburgh, Edinburgh, UK

    Adrian Bird

  7. Max Planck Institute for Informatics, Saarbrücken, Germany

    Christoph Bock & Thomas Lengauer

  8. University of Ulm, Ulm, Germany

    Bernhard Boehm

  9. Institut D'investigacions Biomediques August Pi I Sunyer, Barcelona, Spain

    Elias Campo

  10. Siena Biotech Spa, Siena, Italy

    Andrea Caricasole

  11. Halo Genomics AB, Uppsala, Sweden

    Fredrik Dahl

  12. Institut D'investigacio Biomedica De Bellvitge, Barcelona, Spain

    Manel Esteller

  13. Centre for Genomic Regulation, Barcelona, Spain

    Xavier Estivill, Thomas Graf & Roderic Guigo

  14. University of Cambridge, Cambridge, UK

    Anne Ferguson-Smith & Willem H Ouwehand

  15. Queen Mary University of London, London, UK

    Jude Fitzgibbon, David Leslie & Vardhman Rakyan

  16. European Bioinformatics Institute, Hinxton, UK

    Paul Flicek

  17. European Research and Project Office GmbH, Saarbrücken, Germany

    Claudia Giehl

  18. Erasmus University Medical Centre Rotterdam, Rotterdam, The Netherlands

    Frank Grosveld

  19. Centro Nacional de Analisis Genomico, Barcelona, Spain

    Ivo Gut

  20. University of Copenhagen, Copenhagen, Denmark

    Kristian Helin & Bo Porse

  21. Sigolis AB, Uppsala, Sweden

    Jonas Jarvius

  22. Universitaetsklinikum Essen, Essen, Germany

    Ralf Küppers

  23. Max Planck Institute for Molecular Genetics, Berlin, Germany

    Hans Lehrach & Martin Vingron

  24. Lund University, Malmo, Sweden

    Åke Lernmark

  25. University of Leipzig, Leipzig, Germany

    Markus Loeffler

  26. Centre National de la Recherche Scientifique, Paris Descartes University, Paris, France

    Elizabeth Macintyre

  27. Sapienza University of Rome, Rome, Italy

    Antonello Mai

  28. Radboud University, Nijmegen, The Netherlands

    Joost HA Martens & Hendrik G Stunnenberg

  29. European Institute of Oncology, Milan, Italy

    Saverio Minucci & Pier Giuseppe Pelicci

  30. Diagenode SA, Liege, Belgium

    Hèléne Pendeville

  31. The Babraham Institute, Cambridge, UK

    Wolf Reik

  32. Genomatix Software GmbH, Munich, Germany

    Martin Schrappe & Martin Seifert

  33. Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

    Dirk Schübeler

  34. Christian-Albrechts-Universitaet Zu Kiel, Kiel, Germany

    Reiner Siebert

  35. Cellzome AG, Heidelberg, Germany

    David Simmons

  36. Institut National de la Sante et de la Recherche Medicale, Marseille, France

    Salvatore Spicuglia

  37. Weizmann Institute of Science, Rehovot, Israel

    Amos Tanay

  38. Barcelona Supercomputing Center, Barcelona, Spain

    David Torrents

  39. Centro Nacional de Investigaciones Oncologicas, Madrid, Spain

    Alfonso Valencia

  40. University Medical Centre Groningen, Groningen, The Netherlands

    Edo Vellenga

  41. University of Saarland, Saarbruecken, Germany

    Jörn Walter

  42. Oxford Nanopore Technologies Ltd., Oxford, UK

    Spike Willcocks

  43. BLUEPRINT Consortium,

    David Adams, Lucia Altucci, Stylianos E Antonarakis, Juan Ballesteros, Stephan Beck, Adrian Bird, Christoph Bock, Bernhard Boehm, Elias Campo, Andrea Caricasole, Fredrik Dahl, Emmanouil T Dermitzakis, Tariq Enver, Manel Esteller, Xavier Estivill, Anne Ferguson-Smith, Jude Fitzgibbon, Paul Flicek, Claudia Giehl, Thomas Graf, Frank Grosveld, Roderic Guigo, Ivo Gut, Kristian Helin, Jonas Jarvius, Ralf Küppers, Hans Lehrach, Thomas Lengauer, Åke Lernmark, David Leslie, Markus Loeffler, Elizabeth Macintyre, Antonello Mai, Joost HA Martens, Saverio Minucci, Willem H Ouwehand, Pier Giuseppe Pelicci, Hèléne Pendeville, Bo Porse, Vardhman Rakyan, Wolf Reik, Martin Schrappe, Dirk Schübeler, Martin Seifert, Reiner Siebert, David Simmons, Nicole Soranzo, Salvatore Spicuglia, Michael Stratton, Hendrik G Stunnenberg, Amos Tanay, David Torrents, Alfonso Valencia, Edo Vellenga, Martin Vingron, Jörn Walter & Spike Willcocks

Authors
  1. David Adams
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  2. Lucia Altucci
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  3. Stylianos E Antonarakis
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  5. Stephan Beck
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  7. Christoph Bock
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  8. Bernhard Boehm
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  9. Elias Campo
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  10. Andrea Caricasole
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  11. Fredrik Dahl
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  12. Emmanouil T Dermitzakis
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  13. Tariq Enver
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  14. Manel Esteller
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  15. Xavier Estivill
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  16. Anne Ferguson-Smith
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  17. Jude Fitzgibbon
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  18. Paul Flicek
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  19. Claudia Giehl
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  20. Thomas Graf
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  21. Frank Grosveld
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  22. Roderic Guigo
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  23. Ivo Gut
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  27. Hans Lehrach
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  29. Åke Lernmark
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  30. David Leslie
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  32. Elizabeth Macintyre
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  33. Antonello Mai
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  34. Joost HA Martens
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  35. Saverio Minucci
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  36. Willem H Ouwehand
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  37. Pier Giuseppe Pelicci
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  38. Hèléne Pendeville
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  39. Bo Porse
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  40. Vardhman Rakyan
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  41. Wolf Reik
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  42. Martin Schrappe
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  43. Dirk Schübeler
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  44. Martin Seifert
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  45. Reiner Siebert
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  46. David Simmons
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  47. Nicole Soranzo
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  48. Salvatore Spicuglia
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  49. Michael Stratton
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  50. Hendrik G Stunnenberg
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  51. Amos Tanay
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  52. David Torrents
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  55. Martin Vingron
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  56. Jörn Walter
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  57. Spike Willcocks
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Corresponding author

Correspondence to Hendrik G Stunnenberg.

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Competing interests

David Simmons (Chief Scientific Officer) is employed by Cellzome Ltd., and has options on Cellzome Shares.

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Cite this article

Adams, D., Altucci, L., Antonarakis, S. et al. BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol 30, 224–226 (2012). https://doi.org/10.1038/nbt.2153

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  • DOI: https://doi.org/10.1038/nbt.2153

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