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Mutation accumulation of the transcriptome

Nature Genetics volume 37, pages 458–460 (2005)Cite this article

A microarray-based study of the nematode Caenorhabditis elegans offers a first glimpse of the effect of mutation accumulation on transcriptional variation. One major conclusion is that stabilizing selection must constrain the divergence of gene expression profiles in natural populations.

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Figure 1: Schematic of a mutation accumulation experiment for gene expression.

Katie Ris

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  1. the Department of Genetics, North Carolina State University, Raleigh, 27695-7614, North Carolina, USA

    Greg Gibson

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  1. Greg Gibson
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Gibson, G. Mutation accumulation of the transcriptome. Nat Genet 37, 458–460 (2005). https://doi.org/10.1038/ng0505-458

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