Issue 14, 2010
From the journal:

Soft Matter

Viscosity and interfacial properties in a mussel-inspired adhesive coacervate†

Dong Soo Hwang,‡*a   Hongbo Zeng,‡*bc   Aasheesh Srivastava,a   Daniel V. Krogstad,a   Matthew Tirrell,abd   Jacob N. Israelachviliab  and  J. Herbert Waitee  

* Corresponding authors

a Materials Research Laboratory, University of California, Santa Barbara, California, USA
E-mail: dshwang@mrl.ucsb.edu
Fax: +1-805-893-7998
Tel: +1-805-893-5787

b Department of Chemical Engineering, University of California, Santa Barbara, California, USA
E-mail: hongbo.zeng@ualberta.ca
Fax: +1-780-492-2881
Tel: +1-780-492-1044

c Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta, Canada

d Departments of Bioengineering, Chemical Engineering and Materials Science & Engineering, Materials Science Division, Lawrence Berkeley Laboratory, University of California, Berkeley, CA, USA

e Department of Molecular, Cell, and Developmental Biology, University of California, Santa Barbara, California, USA

Abstract

The chemistry of mussel adhesion has commanded the focus of much recent research activity on wet adhesion. By comparison, the equally critical adhesive processing by marine organisms has been little examined. Using a mussel-inspired coacervate formed by mixing a recombinant mussel adhesive protein (fp-151-RGD) with hyaluronic acid (HA), we have examined the nanostructure, viscosity, friction, and interfacial energy of fluid-fluid phase-separated coacervates using the surface forces apparatus and microscopic techniques. At mixing ratios of fp-151-RGD:HA resulting in marginal coacervation, the coacervates showed shear-thickening viscosity and no structure by cryo-transmission electron microscopy (cryo-TEM). However, at the mixing ratio producing maximum coacervation, the coacervate showed shear-thinning viscosity and a transition to a bicontinuous phase by cryo-TEM. The shear-thinning viscosity, high friction coefficient (>1.2), and low interfacial energy (<1 mJ m−2) observed at the optimal mixing ratio for coacervation are promising delivery, spreading and adhesion properties for future wet adhesive and coating technologies.

Graphical abstract: Viscosity and interfacial properties in a mussel-inspired adhesive coacervate

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Article information

DOI
https://doi.org/10.1039/C002632H
Article type
Paper
Submitted
08 Feb 2010
Accepted
15 Mar 2010
First published
14 May 2010

Soft Matter, 2010,6, 3232-3236

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Viscosity and interfacial properties in a mussel-inspired adhesive coacervate

D. S. Hwang, H. Zeng, A. Srivastava, D. V. Krogstad, M. Tirrell, J. N. Israelachvili and J. H. Waite, Soft Matter, 2010, 6, 3232 DOI: 10.1039/C002632H

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