Issue 13, 2013
From the journal:

Soft Matter

Nanostructured bicontinuous cubic lipid self-assembly materials as matrices for protein encapsulation

Charlotte E. Conn*a  and  Calum J. Drummond*a  

* Corresponding authors

a CSIRO Materials Science and Engineering (CMSE), Private Bag 10, Clayton South MDC, VIC 3169, Australia
E-mail: charlotte.conn@csiro.au, calum.drummond@csiro.au

Abstract

We review the use of bicontinuous cubic amphiphile self-assembly materials for protein encapsulation. The unique amphiphilic nature of bicontinuous cubic lipidic phases make them an ideal medium for the encapsulation of soluble, peripheral, and integral membrane proteins. Current and prospective applications for such systems include drug delivery, membrane protein crystallisation, biosensors and biofuel cells. We focus on the impact of the incorporated protein on the structure of the cubic phase, which has a knock-on effect on performance for many end-applications.

Graphical abstract: Nanostructured bicontinuous cubic lipid self-assembly materials as matrices for protein encapsulation

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Article information

DOI
https://doi.org/10.1039/C3SM27743G
Article type
Review Article
Submitted
28 Nov 2012
Accepted
09 Jan 2013
First published
21 Jan 2013

Soft Matter, 2013,9, 3449-3464

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Nanostructured bicontinuous cubic lipid self-assembly materials as matrices for protein encapsulation

C. E. Conn and C. J. Drummond, Soft Matter, 2013, 9, 3449 DOI: 10.1039/C3SM27743G

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