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Strong Association of Socioeconomic Status and Genetic Ancestry in Latinos: Implications for Admixture Studies of Type 2 Diabetes

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Abstract

In comparison with the European American population, minority groups in the United States experience a disproportionate burden of type 2 diabetes (Carter et al. 1996). This is particularly evident in some Native American tribes, with the Pima Indians presenting one of the highest population prevalences of type 2 diabetes ever reported for any ethnic group (Bennett et al. 1971; Hamman et al. 1978; Knowler et al. 1990). A similar trend can be observed among the admixed populations of Mexico, the Caribbean, and Central and South America (including recent immigrants to the United States), who are commonly characterized as Latinos. Indeed, the risk of type 2 diabetes is twofold to fivefold higher in Latinos from Puerto Rico, Texas, New Mexico, or Colorado (Stern et al. 1981; Hanis et al. 1983; Samet et al. 1988; Hamman et al. 1989; Flegal et al. 1991) than in whites, an epidemiological difference that persists after adjusting for other traits such as abdominal obesity (Haffner et al. 1986).

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Authors

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Sahra Gibbon Ricardo Ventura Santos Mónica Sans

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© 2011 Sahra Gibbon, Ricardo Ventura Santos, and Mónica Sans

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Florez, J.C. et al. (2011). Strong Association of Socioeconomic Status and Genetic Ancestry in Latinos: Implications for Admixture Studies of Type 2 Diabetes. In: Gibbon, S., Santos, R.V., Sans, M. (eds) Racial Identities, Genetic Ancestry, and Health in South America. Palgrave Macmillan, New York. https://doi.org/10.1057/9781137001702_7

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